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Literature summary extracted from
- Inhibition of camel lens zeta-crystallin/NADPH:quinone oxidoreductase by pyridoxal-5'-phosphate (1998), Biochim. Biophys. Acta, 1388, 175-180.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.6.5.5 | additional information | the results of the inhibition studies suggest that an essential Lys is located in the vicinity of the NADPH binding site | Camelus dromedarius | |
| 1.6.5.5 | o-phthalaldehyde | - |
Camelus dromedarius |  |
| 1.6.5.5 | pyridoxal-5'-phosphate | inactivation follows pseudo-first-order kinetics. NADPH protects against inactivation, 9,10-phenanthrenequinone does not protect. Inhibition is uncompetitive with NADPH and non-competitive with respect to 9,10-phenanthrenequinone | Camelus dromedarius | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.6.5.5 | Camelus dromedarius | - |
camel | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.6.5.5 | lens | - |
Camelus dromedarius | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.6.5.5 | 9,10-phenanthrenequinone + NADPH | - |
Camelus dromedarius | 9,10-phenanthrenesemiquinone + NADP+ | - |
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